Tracing Stem Cell Division in Adult Neurogenesis

Lineage tracing quantification reveals symmetric stem cell division in Drosophila male germline stem cells.

In the homeostatic state, adult stem cells divide either symmetrically to increase the stem cell number to compensate stem cell loss, or asymmetrically to maintain the population while producing differentiated cells. We have investigated the mode of stem cell division in the testes of Drosophila melanogaster by lineage tracing and confirm the presence of symmetric stem cell division in this sys...

Adult stem cell lineage tracing and deep tissue imaging

Lineage tracing is a widely used method for understanding cellular dynamics in multicellular organisms during processes such as development, adult tissue maintenance, injury repair and tumorigenesis. Advances in tracing or tracking methods, from light microscopy-based live cell tracking to fluorescent label-tracing with two-photon microscopy, together with emerging tissue clearing strategies an...

Low Intensity Ultrasound, Proliferation & Growth Indexes in Adult Stem Cell

Alcohol, neural stem cells, and adult neurogenesis.

Recent research demonstrates that neural stem cells divide throughout life and give rise to new neurons, a process known as neurogenesis. This article addresses two principal questions concerning alcohol and adult neurogenesis: To what extent are neurogenesis in the adult brain and the risk for alcoholism governed by similar factors? And, to what extent and through what mechanisms do alcohol us...

Adult Hippocampal Neurogenesis and Memory

Adult neurogenesis, a concept emergent in the late 1990s, is the generation of new neurons in the adult brain. This process occurs thank to cells who have this proliferative feature, named as Neural Stem Cells (NSCs). Neural Stem Cells (NSCs) are primary progenitors who can generate the two neural types (neurons and glia). Classically it was assumed that NSCs are only present in the embryo, but...